Thermo Fisher Scientific ZBTB5 Polyclonal Antibody
ZBTB5 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot과 Immunoprecipitation에 적합합니다. 세포 주기 조절 관련 연구에 활용 가능하며, 4°C에서 보관하고 1년의 권장 보관 기간을 가집니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between 275 and 325 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The ZBTB family of proteins comprises diverse zinc finger proteins containing a BTB (BR-C, ttk, and bab) domain. ZBTB5 was identified through sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. It binds DNA and represses transcription of the cell cycle arrest gene p21. ZBTB5 interacts with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, leading to histone deacetylation (Ac-H3 and Ac-H4) at the proximal promoter. This activity promotes cell proliferation and cell cycle progression, suggesting ZBTB5 may function as a potential proto-oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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