Thermo Fisher Scientific ZBTB5 Polyclonal Antibody
ZBTB5 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며 1:1,000 희석 비율 권장. 세포주기 조절 관련 연구에 적합. 4°C에서 보관하며 1년의 유효기간을 가짐.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between 275 and 325 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The ZBTB family of proteins consists of zinc finger proteins containing a BTB (BR-C, ttk, and bab) domain. ZBTB5 was identified as a POZ domain Kruppel-like zinc finger (POK) protein. It binds DNA and represses transcription of the cell cycle arrest gene p21. ZBTB5 interacts with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, leading to histone deacetylation (Ac-H3 and Ac-H4) at the promoter region. It promotes cell proliferation and cycle progression, suggesting a potential proto-oncogene role.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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