
Thermo Fisher Scientific PDE1B Polyclonal Antibody
PDE1B 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 인간과 생쥐 시료에 반응합니다. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PDE1B (Accession Q01064), corresponding to amino acid residues E498–D536 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853011 |
Product Specific Information
This antibody detects endogenous levels of total PDE1B.
Target Information
The PDE1B protein belongs to the cyclic nucleotide phosphodiesterase (PDE) family, specifically the PDE1 subfamily. Members of this family are calmodulin-dependent PDEs activated by the calcium-calmodulin complex. PDE1B exhibits dual specificity for cAMP and cGMP, with a preference for cGMP as a substrate. These cyclic nucleotides regulate numerous physiological processes. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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