Thermo Fisher Scientific Syndecan 4 Recombinant Rabbit Monoclonal Antibody (112)
Recombinant rabbit monoclonal antibody specific to Mouse Syndecan-4 (SDC4). Validated for Western blot and flow cytometry. Offers high specificity, lot-to-lot consistency, and preservative-free formulation. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Flow Cytometry (Flow) | 1:25–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 112 |
| Immunogen | Recombinant Mouse Syndecan-4/SDC4 protein (Met1–Val146) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; -20°C long term (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785606 |
Additional Formats
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits, followed by clone screening to select optimal candidates.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to large rabbit immune repertoire
This antibody specifically recognizes Mouse Syndecan-4/SDC4.
Target Information
Syndecans are type I integral membrane proteoglycans involved in cell–extracellular matrix adhesion and growth factor binding.
- Syndecan 1 binds Collagens, Fibronectin, and Thrombospondin.
- Syndecan 1 and 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis.
- Syndecan 2 is highly expressed in regions of high morphogenetic activity such as epithelial-mesenchymal interfaces.
- Syndecan 4 cooperates with integrins in cell spreading and focal adhesion assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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