Thermo Fisher Scientific Fibrinogen Monoclonal Antibody (1F3)
인체 Fibrinogen을 검출하는 Mouse monoclonal antibody (Clone 1F3). Western blot 및 ELISA에 사용 가능하며, Protein A로 정제된 5 mg/mL 액상 형태. PBS(pH 7.4) 완충액에 0.09% sodium azide 포함, 4°C 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| ELISA | Assay-dependent | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F3 |
| Immunogen | Fibrin degradation products |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_558927 |
Product Specific Information
MA1-20038 detects fibrinogen in human samples.
Target Information
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, which is the most abundant component of blood clots.
Fibrinogen consists of a dimer of three pairs of non-identical chains (FGA, FGB, and FGG) that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has two terminal D domains and one central E domain; all three domains are separated when fibrinogen is degraded by plasmin.
Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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