Thermo Fisher Scientific Fibrinogen Monoclonal Antibody (15E11)
인간 피브리노겐을 검출하는 Mouse monoclonal antibody (Clone 15E11). Western blot 및 ELISA에 사용 가능. 액상 형태로 제공되며, 4°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 15E11 |
| Immunogen | Fibrin degradation products |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.4 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_558925 |
Product Specific Information
MA1-20036 detects fibrinogen in human samples.
Target Information
Fibrinogen, the precursor of fibrin, is a coagulable protein found in vertebrate blood plasma. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the major component of blood clots.
Fibrinogen is a dimer composed of three pairs of non-identical chains (FGA, FGB, and FGG) cross-linked by disulfide bonds in their N-terminal segments. The molecule contains two terminal D domains and one central E domain, which separate when degraded by plasmin.
Mutations in this gene can cause disorders such as dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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