Thermo Fisher Scientific Fibrinogen Monoclonal Antibody (27C8)
인간 피브리노겐을 인식하는 마우스 단클론 항체로, Western blot 및 ELISA에 사용 가능. 단백질 A로 정제된 액상 제형이며, 4°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Assay-dependent
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 27C8 |
| Immunogen | Fibrin degradation products |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.3 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_558928 |
Product Specific Information
MA1-20039 detects fibrinogen in human samples.
Target Information
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the most abundant component of blood clots.
Fibrinogen consists of a dimer of three pairs of non-identical chains (FGA, FGB, FGG) cross-linked by disulfide bonds at their N-terminal segments. The molecule has two terminal D domains and one central E domain, which are separated when fibrinogen is degraded by plasmin.
Mutations in this gene can cause disorders such as dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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