Thermo Fisher Scientific TTLL8 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TTLL8. Recombinant protein control fragment (Product #RP-91398).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649101

Product Specific Information

Immunogen sequence: SLEIGLCVNM RSLPWYVPAN PDSFFPRCYS LCTESEQQEF LEDFRRTMAS SILKWVVSHQ SCSRSSRSKP RDQREEAGSS DLSSRQDAEN AEAKLRGLPG QLVDIACKVC QAYLGQLEHE DIDTSADAVE DLTEAEWEDL TQQYYSLVHG DAFISNSRNY FSQCQALLNR ITSVNPQTDI DGLRNIWII

Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 59%.

Target Information

Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.