
Thermo Fisher Scientific NEK11 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NEK11 protein. Validated for IHC (P) and ICC/IF applications. Antigen affinity purified, supplied in PBS with 40% glycerol. Suitable for DNA replication and genotoxic stress studies. For research use only.
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- PA553516
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NEK11. Recombinant protein control fragment (Product #RP-89776). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644603 |
Product Specific Information
Immunogen sequence:
DFGVSRLLMG SCDLATTLTG TPHYMSPEAL KHQGYDTKSD IWSLACILYE MCCMNHAFAG SNFLSIVLKI VEGDTPSLPE RYPKELNAIM ESMLNKNPSL RPSAIEILKI PYLDEQLQNL MC
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 82%
Target Information
NEK11 (FLJ23495) belongs to the NIMA family of kinases involved in DNA replication and genotoxic stress response. NEK11 encodes a nucleolar protein that may function with NEK2A in the S-phase checkpoint. It plays roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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