Thermo Fisher Scientific NEK11 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NEK11. Recombinant protein control fragment (Product #RP-89776). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NEK11,uniProtId:Q8NG66-1,ncbiNodeId:9606,antigenRange:175-296,antigenLength:645,antigenImageFileName:PA5-53516_NEK11_Q8NG66-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53516_NEK11_Q8NG66-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644603

Product Specific Information

Immunogen sequence: DFGVSRLLMG SCDLATTLTG TPHYMSPEAL KHQGYDTKSD IWSLACILYE MCCMNHAFAG SNFLSIVLKI VEGDTPSLPE RYPKELNAIM ESMLNKNPSL RPSAIEILKI PYLDEQLQNL MC

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 82%.

Target Information

NEK11 (FLJ23495) belongs to the NIMA family of kinases which are involved in DNA replication and genotoxic stress response. NEK11 encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.