Thermo Fisher Scientific CPOX Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human CPOX. Recombinant protein control fragment (Product #RP-106543). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CPOX,uniProtId:P36551-1,ncbiNodeId:9606,antigenRange:319-453,antigenLength:454,antigenImageFileName:PA5-65872_CPOX_P36551-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65872_CPOX_P36551-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2662825

Product Specific Information

Immunogen sequence: CDDYFFIAHRG ERRGIGGIFF DDLDSPSKEE VFRFVQSCAR AVVPSYIPLV KKHCDDSFTP QEKLWQQLRR GRYVEFNLLY DRGTKFGLFT PGSRIESILM SLPLTARWEY MHSPSENSKE AEILEVLRHP RDWV

Highest antigen sequence identity to the following orthologs - mouse 91%, rat 92%.

Target Information

The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.