
Thermo Fisher Scientific Phospho-Muscle Glycogen Synthase (Ser641) Polyclonal Antibody
인산화된 인간 근육 글리코겐 합성효소(Ser641)를 특이적으로 인식하는 Rabbit Polyclonal 항체. WB, IHC, ELISA, IP 등 다양한 응용에 적합. 인산화 비특이적 반응이 1% 미만으로 높은 특이성 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| ELISA | 1:5,000–1:25,000 |
| Immunoprecipitation (IP) | 1:500–1:3,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human Muscle Glycogen Synthase phospho peptide corresponding to pS641 region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid repeated freeze/thaw cycles.
- Centrifuge if solution is not clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
Phospho Glycogen Synthase pS641 antibody is directed against human muscle glycogen synthase. This phospho-specific polyclonal antibody recognizes phosphorylated pS641 of human muscle glycogen synthase with less than 1% cross-reactivity to non-phosphorylated form by ELISA. Cross-reactivity occurs in mouse tissue; reactivity in other species is not determined.
Target Information
Glycogen Synthase 1 (GYS1) catalyzes the addition of glucose monomers to the growing glycogen molecule through formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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