Thermo Fisher Scientific GPR120 Polyclonal Antibody
GPR120 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P) 등 다양한 응용에 적합하며, 고순도 1 mg/mL 액상 형태로 제공. 장기 보관 시 -20°C에서 안정적으로 유지 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 10–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 5th transmembrane domain of human O3FAR1 / GPR120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2551393 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Monkey, Marmoset, Mouse, Rat, Elephant, Horse, Opossum (94%)
Bat, Panda, Pig (89%)
Turkey (83%)
Target Information
An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist.
All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms.
An array of activating ligands participate in the conformation of GPCRs, leading to signaling via G-proteins and downstream effectors.
Ongoing studies have shown complex reactions involved in negative regulation of GPCRs, which have significant physiological implications and drive pharmacological research for new drug candidates.
Notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough), which dominate the mental health and allergy markets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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