Thermo Fisher Scientific CD9 Polyclonal Antibody
CD9 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, Flow Cytometry에 적합합니다. 인간과 생쥐 시료에서 검증되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 세포 부착, 분화, 신호전달 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | 1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:200 | View 2 publications |
| Flow Cytometry (Flow) | 1:100–1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within Human CD9 (amino acids 21–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2802756 |
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
CD9 belongs to the tetraspanin family, which spans the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation, possibly through association with integrin CD41/CD61 (GPIIb/GPIIIa).
It is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion. CD9 plays roles in cell attachment, proliferation, and is essential for MHC II molecule association on dendritic cells, crucial for T cell stimulation.
CD9 functions in differentiation, adhesion, and signal transduction, and its expression is linked to suppression of cancer cell motility and metastasis, acting as a metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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