Thermo Fisher Scientific ESRRA Monoclonal Antibody (OTI1C6), TrueMAB
Human ESRRA 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화됨. 1 mg/mL 농도의 액상 형태이며, PBS/BSA/glycerol 버퍼에 보관. ESRRA의 대사 조절 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 206–417 of human ESRRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All ERR family members share an almost identical DNA-binding domain, showing 68% amino acid identity with that of the estrogen receptor.
ERRα binds to an ERR-alpha response element (ERRE) containing a single consensus half-site (5'-tnaaggtca-3') and can also bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1.
It functions as a metabolic regulator and is often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for ERR1 is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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