ELK Biotechnology Histone H3 (phospho Thr3) rabbit pAb
Histone H3 (phospho Thr3) 인산화 부위를 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, ELISA에 적합합니다. 핵 및 염색체에 위치한 Histone H3 단백질 연구에 활용되며, 높은 특이도와 재현성을 제공합니다.
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제품명
Histone H3 (phospho Thr3) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Histone H3 around the phosphorylation site of Thr3 (AA range: 1–50) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 20 kDa |
| GeneID (Human) | 8350 / 8351 / 8352 / 8353 / 8354 / 8355 / 8356 / 8357 / 8358 / 8968 |
| Human Swiss-Prot No | P68431 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human; Mouse; Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through interaction of a linker histone (H1) with DNA between nucleosomes to form higher-order chromatin structures.
This gene is intronless and encodes a replication-dependent histone that belongs to the histone H3 family. Transcripts from this gene lack polyA tails and instead contain a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6p22-p21.3. (RefSeq, Aug 2015)
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