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ELK Biotechnology Caldesmon rabbit pAb
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Caldesmon 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 사람, 생쥐, 랫트 시료에 반응하며 세포질 및 세포골격에 위치한 단백질 검출에 유용합니다. -20°C에서 1년 보관 가능합니다.
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- pk
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ELK Biotechnology ES7606-100UL Caldesmon rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES7606-50UL Caldesmon rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Caldesmon rabbit pAb
Caldesmon rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Caldesmon rabbit pAb |
| Alternative Names | CALD1; CAD; CDM; Caldesmon; CDM |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caldesmon. AA range: 725-774 |
| Species Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 93 kD |
| GeneID (Human) | 800 |
| Human Swiss-Prot No | Q05682 |
| Cellular Localization | Cytoplasm, cytoskeleton; cytoplasm, myofibril; cytoplasm, cytoskeleton, stress fiber. On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle). |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids.
This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction.
Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
[provided by RefSeq, Jul 2008]
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