ELK Biotechnology UBF rabbit pAb
UBF rabbit pAb는 인간, 마우스, 랫트에서 반응하는 폴리클로날 항체로, 핵 및 인핵 내 UBF 단백질 검출에 적합합니다. Western blot과 ELISA에 사용 가능하며, UBF 유래 합성 펩타이드로 면역화되었습니다. -20°C에서 1년 보관 가능합니다.
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제품명
UBF rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | UBTF; UBF; UBF1; Nucleolar transcription factor 1; Autoantigen NOR-90; Upstream-binding factor 1; UBF-1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from UBF (AA range: 420–500) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 89 kD |
| GeneID (Human) | 7343 |
| Human Swiss-Prot No | P17480 |
| Cellular Localization | Nucleus, nucleolus |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. It may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed. Pseudogenes are located on the short arm of chromosomes 3, 11, and X and the long arm of chromosome 11. (provided by RefSeq, Aug 2011)
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