ELK Biotechnology TGFβ RIII (phospho Thr842) rabbit pAb
TGFβ RIII (phospho Thr842) rabbit polyclonal antibody로 인간, 마우스, 랫트 시료에 반응합니다. IHC, IF, ELISA에 사용 가능하며, Thr842 인산화 부위에 특이적으로 결합합니다. -20°C에서 1년 보관 가능하며, 고품질 IgG 폴리클로날 항체입니다.
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제품명
TGFβ RIII (phospho Thr842) rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | TGFBR3; Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TGF beta Receptor III around the phosphorylation site of Thr842. AA range: 801–850 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 7049 |
| Human Swiss-Prot No | Q03167 |
| Species Reactivity | Human; Mouse; Rat |
세포 내 위치 (Cellular Localization)
Secreted; extracellular space; cell membrane; single-pass type I membrane protein. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
배경 (Background)
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members.
Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling.
Decreased expression of this receptor has been observed in various cancers.
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
[provided by RefSeq, Sep 2010]
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