Thermo Fisher Scientific MFN1 Monoclonal Antibody (OTI2E4), TrueMAB
MFN1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 인간 MFN1(aa 209–469) 재조합 단백질을 면역원으로 사용하였으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능하며, 미토콘드리아 융합 및 세포 사멸 관련 연구에 유용합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MFN1 Monoclonal Antibody (OTI2E4), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 209–469 of human MFN1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Mitofusin 1 (MFN1) and its related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism. They may be associated with obesity and/or apoptosis processes.
MFN1 and MFN2 form homotypic and heterotypic complexes, coordinating mitochondrial fusion and essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in Bax but not its mitochondrial translocation, suggesting MFN1 regulates Bax activation on the outer mitochondrial membrane.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.