Thermo Fisher Scientific Cardiac Troponin T Monoclonal Antibody (1G1)
Cardiac Troponin T 단백질을 검출하기 위한 Mouse IgG1 단클론 항체. Western blot, Flow cytometry, ELISA에 적합. Human 시료에 반응하며 36kDa 단백질을 인식. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Flow Cytometry (Flow) | 1:200–1:400 | View 1 publication |
| ELISA | 1:10,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G1 |
| Immunogen | Purified recombinant fragment of human troponin T2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2538663 |
Product Specific Information
MA5-17192 targets troponin T2 in indirect ELISA, FACS, and WB applications and shows reactivity with human samples.
The MA5-17192 immunogen is a purified recombinant fragment of human troponin T2 expressed in E. coli.
MA5-17192 detects troponin T2, which has a predicted molecular weight of approximately 36 kDa.
Target Information
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, located on the thin filament of striated muscles. It regulates muscle contraction in response to intracellular calcium ion concentration changes.
Cardiac Troponin T is essential for proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner.
Expression of Cardiac Troponin T is affected by heart failure. Mutations in this protein are associated with familial hypertrophic cardiomyopathy and dilated cardiomyopathy.
Alternative splicing of the Cardiac Troponin T gene produces many tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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