Thermo Fisher Scientific ABCG1 Polyclonal Antibody
인간 ABCG1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태. 콜레스테롤 대사 연구 및 ABC 수송체 기능 분석에 유용.
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Thermo Fisher Scientific ABCG1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ABCG1. Recombinant protein control fragment (Product #RP-95337). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637540 |
Product Specific Information
Immunogen sequence:
AEMTEPKSVC VSVDEVVSSN MEATETDLLN GHLKKVDNNL TEAQRFSSLP RRAAVNIEFR DLSYSVPEGAntigen sequence identity:
Mouse – 90%
Rat – 90%
Target Information
ATP-binding cassette (ABC) transporter genes regulate dietary cholesterol retention.
ABCG1 (also known as ABC8) is expressed on the cell surface and intracellular compartments of cholesterol-laden macrophages.
Its expression is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein, while HDL(3)-mediated lipid efflux suppresses ABCG1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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