Thermo Fisher Scientific CAZIP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CAZIP. Recombinant protein control fragment (Product #RP-94984). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CAZIP,uniProtId:Q5JR59-2,ncbiNodeId:9606,antigenRange:527-620,antigenLength:1369,antigenImageFileName:PA5-56758_CAZIP_Q5JR59-2_Rabbit.svg,antigenImageFileNamePDP:PA5-56758_CAZIP_Q5JR59-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639322

Product Specific Information

Immunogen sequence: DSVLNIPAPL HPETTVNMTY QPTTPSSSFQ DVSVFGMDAG SPLVVPPPTD SARLLNTSPK VPDKNTCPSG IPKPVFTHSK DTPSSQEGME NYQV

Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 62%.

Target Information

CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.