Thermo Fisher Scientific CAZIP Polyclonal Antibody
Human CAZIP 단백질을 인식하는 Rabbit IgG 폴리클로날 항체로, IHC(P)에서 1:20~1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CAZIP. Recombinant protein control fragment (Product #RP-94985) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639323 |
Product Specific Information
- Immunogen sequence:
TYIRRNPQAL GQVDASLVPV GLPYAPPTCT MPLPHEEKAA GGDLKPSANL YEKFKPDLQK PRVFSSGLMV SGIKPPGHPF SQMSEKFLQE VTDHPG - Highest antigen sequence identity to orthologs:
- Mouse: 86%
- Rat: 83%
Target Information
CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms.
CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development.
It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules.
CAZIP may regulate the dynamics of microtubules at their growing distal tip.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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