Thermo Fisher Scientific AKAP12/Gravin Polyclonal Antibody
AKAP12/Gravin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성, 액상 형태, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
- Reference: 없음
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
- Reference: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1650 and 1700 of human A kinase (PRKA) anchor protein (gravin) 12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins that bind to the regulatory subunit of protein kinase A (PKA) and localize the holoenzyme to discrete cellular regions.
This gene encodes an AKAP family member expressed in endothelial cells, fibroblasts, and osteosarcoma cells. It associates with kinases A and C, phosphatase, and functions as a scaffold protein in signal transduction.
AKAP12 and RII PKA colocalize at the cell periphery and are related to cell growth. Antibodies to this protein may be produced in patients with myasthenia gravis.
Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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