Thermo Fisher Scientific Phospho-VPS34 (Ser282) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phospho-VPS34 (Ser282). Validated for dot blot at 1:500 dilution. Predicted cross-reactivity with mouse, rat, and Xenopus. Suitable for studying PI3KC3 signaling, autophagy, and intracellular trafficking.
- 카탈로그번호
- PA512798
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-VPS34 (Ser282) Polyclonal Antibody
Applications
- Dot blot (DB): 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S282 of human PI3KC3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2165123 |
Product Specific Information
This antibody is predicted to react with mouse, rat, and Xenopus based on sequence homology.
Target Information
PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. It phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes.
PIK3C3 is involved in coupling nutrient signaling to mTOR, and plays a role in autophagy and intracellular trafficking. It regulates degradative endocytic trafficking and is required for the abscission step in cytokinesis, likely in the context of PI3KC3-C2. It is also essential for the transport of lysosomal enzyme precursors from early to late endosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.