Thermo Fisher Scientific Phospho-JNK/SAPK1 (Thr183, Tyr185) Polyclonal Antibody
인간 및 랫트 JNK/SAPK1 인산화 상태(Thr183, Tyr185)를 검출하는 폴리클로날 항체. Western blot에 적합하며, 고순도 항원 친화 크로마토그래피로 정제됨. 액상 형태로 안정적이며 단기 4°C, 장기 -20°C 보관 가능. 연구용 전용 시약.
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Thermo Fisher Scientific Phospho-JNK/SAPK1 (Thr183, Tyr185) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.1–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide surrounding the epitope -TPY- with dual phosphorylation sites at Thr183 and Tyr185 of human JNK/SAPK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 25 mM Tris with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: UV-treated HEK293 cells
- Cellular Location: Cytoplasm
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are serine-threonine protein kinases activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus.
JNK is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development. It is activated by stress and inflammatory signals and expressed as ten isoforms due to differential mRNA splicing, with JNK1 and JNK2 being the predominant forms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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