Thermo Fisher Scientific ANKMY2 Polyclonal Antibody
ANKMY2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. 인간 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS(2% sucrose) 버퍼에 0.09% sodium azide를 포함하고 있으며, -20°C에서 보관합니다.
- 카탈로그번호
- PA570312
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human ANKMY2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689441 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Target Information
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, and C. elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, suggests that ANKMY2 may play a role in the pathogenesis of NK-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which hinders hemopoiesis, diverts differentiation to an alternative fate, and promotes pre-leukemic states.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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