Thermo Fisher Scientific CPA6 Polyclonal Antibody
Thermo Fisher Scientific의 CPA6 폴리클로날 항체는 인간 CPA6 단백질을 인식하며 Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었고, 액상 형태로 0.5 mg/mL 농도를 유지합니다. 아지드 보존제로 안정화되어 있으며 연구용으로만 사용됩니다.
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Thermo Fisher Scientific CPA6 Polyclonal Antibody
Applications
- Western Blot (WB): 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human CPA6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689006 |
Product Specific Information
This target displays homology in the following species:
Cow: 93% • Dog: 93% • Guinea Pig: 100% • Horse: 93% • Human: 100% • Mouse: 100% • Rabbit: 93% • Rat: 100% • Zebrafish: 100%
Target Information
Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure, function, and amino acid sequence similarity.
As a member of the A/B subfamily, CPA6 (Carboxypeptidase A6) is a 437 amino acid secreted, zinc-binding protein containing a propetide at the amino terminus, cleaved upon activation.
CPA6 is broadly expressed in embryonic tissues and highly in the adult olfactory bulb and epididymis. It cleaves large C-terminal hydrophobic residues from proteins and substrates, likely contributing to extracellular neuropeptide processing.
Mutations in CPA6 are linked to Duane syndrome, a congenital eye movement disorder involving abnormal development of cranial nerve VI (abducens nerve).
Three isoforms of CPA6 exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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