Thermo Fisher Scientific RIP3 Recombinant Superclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Mouse, Rat, and Horse.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple different recombinant monoclonal antibodies, providing the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies, all with consistent recombinant production.
These antibodies recognize multiple epitopes on the target, offering higher detection sensitivity for low-abundance targets, while maintaining reproducibility across lots.
Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.

Target Information

RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine kinases, containing a unique C-terminal domain. It is predominantly localized in the cytoplasm and mitochondria, capable of nucleocytoplasmic shuttling.
RIPK3 participates in TNF receptor-I signaling, can induce apoptosis, and weakly activate NF-kappaB. Caspase-8 prevents RIPK3-dependent necrosis by forming a proteolytically active complex with CFLAR, which is essential for its protective function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.