Thermo Fisher Scientific MAP2 Monoclonal Antibody (5B7)
Human MAP2 단백질을 검출하기 위한 Mouse IgG1 단클론 항체로, WB, Flow Cytometry, ELISA에 적합합니다. 정제된 재조합 MAP2(aa 24-123)를 면역원으로 사용하며, Protein G로 정제된 액상형 항체입니다. 신경세포 구조 및 알츠하이머병 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5B7 |
| Immunogen | Purified recombinant fragment of human MAP2 (amino acids 24–123) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538587 |
Product Specific Information
MA5-17116 targets MAP2 in FACS, indirect ELISA, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human MAP2 (amino acids 24–123) expressed in E. coli.
MA5-17116 detects MAP2 with a predicted molecular weight of approximately 199 kDa.
Target Information
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a and MAP2b) and a low molecular weight form. Its expression is developmentally regulated, and multiple forms arise by alternative splicing of a single gene.
MAP2 plays a crucial role in microtubule assembly, an essential step in neurogenesis. In rat and mouse, MAP2 products are neuron-specific cytoskeletal proteins enriched in dendrites, contributing to dendritic shape stabilization during neuron development.
MAP2 is useful for studies of neuronal structure in normal and malignant brain tissue and in degenerative diseases such as Alzheimer’s Disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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