Thermo Fisher Scientific H2BK20ac Recombinant Rabbit Monoclonal Antibody (PS01-46)
H2BK20ac 타깃의 재조합 토끼 단클론 항체로 Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. HEK293 발현, Protein A 정제. 핵 내 히스톤 H2B 아세틸화 연구에 적합.
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Thermo Fisher Scientific H2BK20ac Recombinant Rabbit Monoclonal Antibody (PS01-46)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PS01-46 |
| Immunogen | Synthetic peptide surrounding acetylated Lys5 of human histone H2B protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3094434 |
Product Specific Information
- Positive control: Hela treated with 500 ng/mL TSA for 4 hours whole cell lysate, human colon carcinoma tissue, human skin tissue, mouse skin tissue, rat skin tissue, Hela, NIH/3T3
- Predicted band size: 14 kDa
- Subcellular Location: Nucleus, Chromosome
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). These structures compact DNA into chromatin, regulating accessibility for transcription, repair, replication, and maintaining chromosomal stability. H2B also exhibits broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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