Thermo Fisher Scientific RXRA Polyclonal Antibody

Applications and Tested Dilution

Immunohistochemistry (Paraffin) (IHC (P))

• Dilution: 1:100–1:1,000

Immunocytochemistry (ICC/IF)

• Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Predicted Reactivity: Rat (96%), Bovine (86%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells.
The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors.
RAs have been suggested to potentially play a therapeutic role in cervical cancer. They are also known to play key roles in neuronal development, with evidence indicating that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.