Thermo Fisher Scientific PAK4 Polyclonal Antibody
PAK4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunoprecipitation에 적합하며, 세포골격 재구성 및 암 관련 신호 연구에 활용 가능. 액상 형태로 제공되며 4°C에서 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 and 75 of human p21-Activated Kinase 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
PAK4 is a serine/threonine p21-activated kinase involved in actin cytoskeleton reorganization and filopodia formation. It belongs to the second group of PAKs (PAK4, 5, and 6), which are not activated by Cdc42/Rac binding. PAK4 acts as an effector of Cdc42Hs, inducing filopodia and actin polymerization, and plays a key role in cytoskeletal organization, embryonic viability, and neuronal development. It is also implicated in tumor cell growth and activation of cancer prosurvival pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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