Thermo Fisher Scientific YB1 Polyclonal Antibody
YBX1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), IP 등에 적합합니다. 1 mg/mL 액상 형태이며 4°C에서 보관합니다. 다양한 종(Rat, Chicken 등)과 교차 반응이 예측됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 224 and 274 of Human Y Box Binding Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat, X. laevis, Chicken, Bovine, and Rabbit
Target Information
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. It stabilizes cytoplasmic mRNA and modulates translation by influencing interactions with eukaryotic initiation factors. YBX1 binds to promoters containing a Y-box sequence (5'-CTGATTGGCCAA-3'), such as HLA class II genes, and regulates transcription of numerous genes. It promotes separation of DNA strands with mismatches or cisplatin modifications, exhibits endonucleolytic activity, and may play a role in DNA repair.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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