Thermo Fisher Scientific CD44 Monoclonal Antibody (OTI2D9), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CD44 is a 100 kDa type I transmembrane glycoprotein expressed on human leukocytes, brain white matter, and some epithelial cells.
It serves as a receptor for hyaluronic acid (HA) and plays key roles in cell-cell interaction, adhesion, and migration.
CD44 is involved in lymphocyte activation, recirculation, and homing, and its expression can increase in certain carcinomas, potentially linked to metastatic potential.
Multiple isoforms exist due to alternative splicing, contributing to the functional diversity of CD44.
Diseases associated with CD44 dysfunction include superficial keratitis and lichen sclerosus. CD44 may also be implicated in tumor metastasis formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.