
Thermo Fisher Scientific TERT Polyclonal Antibody
Rabbit polyclonal antibody targeting human TERT protein for WB and IHC applications. Recognizes synthetic peptide from aa 910–960 region. Lyophilized form, unconjugated, stored at 4°C short term or -20°C long term. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous (PubMed)
- Publications: 1 available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 910–960 of human Telomerase reverse transcriptase (TERT), conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. Add glycerol (1:1) for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: TERT.
Target Information
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by adding the repeat sequence TTAGGG. It includes a protein component with reverse transcriptase activity (encoded by the TERT gene) and an RNA component that serves as a template. Telomerase expression is typically repressed in postnatal somatic cells, leading to telomere shortening and cellular senescence. Dysregulation may contribute to oncogenesis. Studies suggest telomerase may aid chromosomal repair through de novo synthesis of telomere repeats. Multiple alternatively spliced variants of TERT exist, some with incomplete sequences, indicating complex regulation of telomerase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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