Thermo Fisher Scientific RFC2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Concentration: 1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: WVEKYRPVKL NEIVGNEDTV SRLEVFAREG NVPNIIIAGP PGTGKTTSIL CLARALLGPA LKDAMLELNA SNDRGIDVVR NKIKMFAQQK VTLPKGRHKI IILDEADSMT DGAQQALRRT MEIYSKTTRF ALACNASDKI IEPIQSRCAV LRYTKLTDAQ ILTRLMNVIE KERVPYTDDG LEAIIFTAQG DMRQALNNLQ STFSGFGFIN SENVFKVCDE PHPLLVKEMI QHCVNANIDE AYKILAHLWH LGYSPEDIIG
• Positive Samples: LO2, 22Rv1, Mouse spleen
• Cellular Location: Nucleus

Target Information

This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA), and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits. The RFC2 gene encodes the 40 kD subunit responsible for ATP binding and may promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene exists on chromosome 2.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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