Thermo Fisher Scientific RFC2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 38-297 of human RFC2 (NP_8521361) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RFC2,uniProtId:P35250-1,ncbiNodeId:9606,antigenRange:38-297,antigenLength:354,antigenImageFileName:PA5-93246_RFC2_P35250-1_Rabbit.svg,antigenImageFileNamePDP:PA5-93246_RFC2_P35250-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806691

Product Specific Information

Immunogen sequence: WVEKYRPVKL NEIVGNEDTV SRLEVFAREG NVPNIIIAGP PGTGKTTSIL CLARALLGPA LKDAMLELNA SNDRGIDVVR NKIKMFAQQK VTLPKGRHKI IILDEADSMT DGAQQALRRT MEIYSKTTRF ALACNASDKI IEPIQSRCAV LRYTKLTDAQ ILTRLMNVIE KERVPYTDDG LEAIIFTAQG DMRQALNNLQ STFSGFGFIN SENVFKVCDE PHPLLVKEMI QHCVNANIDE AYKILAHLWH LGYSPEDIIG; Positive Samples: LO2, 22Rv1, Mouse spleen; Cellular Location: Nucleus

Target Information

This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.