Thermo Fisher Scientific Mitofilin Polyclonal Antibody
Mitofilin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, IP에 사용 가능. 다양한 종(인간, 마우스, 랫, 개 등)에 반응. 미토콘드리아 구조 연구에 적합하며, HeLa lysate 등에서 양성 대조로 권장됨.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 1:500 | View 1 publication |
| Immunoprecipitation (IP) | Assay-dependent | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Cat, Human, Mouse, Non-human primate, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length recombinant human Mitofilin protein (UniProt ID: Q16891-1, antigen range: 1–758) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2127191 |
Product Specific Information
- Suggested positive control: HeLa whole cell lysate, dog testis, antigen standard for IMMT (transient overexpression lysate).
Target Information
Mitofilin is a transmembrane protein of the inner mitochondrial membrane associated with a large multimeric protein complex (~1200 kDa).
It plays a critical role in mitochondrial morphology, fusion, and fission, particularly in forming tubular cristae and cristae junctions.
Abnormal mitochondrial morphology has been linked to diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma, and Whartin's tumor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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