Thermo Fisher Scientific Cystatin 8 Polyclonal Antibody
Cystatin 8 단백질을 표적으로 하는 Thermo Fisher Scientific의 고순도 Rabbit Polyclonal Antibody. Western blot, IHC, ICC 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되어 SDS-PAGE 기준 95% 이상 순도. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Cystatin 8 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human Cystatin 8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2719729 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes.
The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily. CRES proteins lack two of the three consensus sites necessary for cystatin inhibition of C1 cysteine proteases. They are preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs.
As a member of the CRES subfamily, Cystatin 8 is a 142-amino-acid protein expressed in the proximal caput region of the epididymis, where it performs a specialized role during sperm development and maturation.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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