Thermo Fisher Scientific GPR6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 253-362 of human GPR6 (NP_0052751) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR6,uniProtId:P46095-1,ncbiNodeId:9606,antigenRange:253-362,antigenLength:362,antigenImageFileName:PA5-90013_GPR6_P46095-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90013_GPR6_P46095-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.3 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805889

Product Specific Information

Immunogen sequence: WRHAHQIALQ QHCLAPPHLA ATRKGVGTLA VVLGTFGASW LPFAIYCVVG SHEDPAVYTY ATLLPATYNS MINPIIYAFR NQEIQRALWL LLCGCFQSKV PFRSRSPSEV; Positive Samples: U-251MG; Cellular Location: Cell membrane, Multi-pass membrane protein

Target Information

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR6 is an orphan, constitutively active G-coupled protein receptor, involved in a wide array of functions such as neurite growth, amyloid processing and appetitive learning. GPR6 is predominantly expressed in neurons in the striatum of the brain. GPR6 was found to be expressed on the cell surface and in intracellular compartments.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.