Thermo Fisher Scientific S100A10 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal 항체로, Western Blot, IHC, ICC/IF에 사용 가능. 합성 펩타이드(aa 30–70)를 면역원으로 제작, 항원 친화 크로마토그래피로 정제됨. 고순도 및 안정적이며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 30–70 of Human S100A10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719160 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The S-100 family of calcium-activated proteins interact with diverse target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular surface, forming a heterotetrameric complex with Annexin II. This association is not required for plasma membrane localization or plasminogen activation.
S-100A10 also acts as a cellular chaperone for hepatitis B virus polymerase, facilitating partial nuclear localization and suggesting a role in viral replication mediated by intracellular calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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