Thermo Fisher Scientific MIDN Polyclonal Antibody
Thermo Fisher Scientific의 MIDN Polyclonal Antibody는 인간 MIDN 단백질을 표적으로 하는 토끼 유래 IgG 항체입니다. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, 신경발생 관련 유전자 연구에 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MIDN. Recombinant protein control fragment (Product #RP-99142) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643968 |
Product Specific Information
Immunogen sequence:
LNDLLSATRH YQGMPPSLAQ LRCHAQCSPA SPAPDLAPRT TSCEKLTAAP SASLLQGQSQ IRMCKPPGDR LRQTENRATR CKVER
Antigen sequence identity:
- Mouse: 92%
- Rat: 88%
Target Information
Expression of the midnolin gene is developmentally regulated and strongly expressed in the mesencephalon (midbrain) of E12.5 mouse embryos.
The midnolin protein (508 aa) contains a ubiquitin-like domain and is localized in the nucleus and nucleolus, not in the cytoplasm.
The nucleolar localization signal is a 28 aa peptide located at the C-terminal region of midnolin.
Midnolin may regulate genes related to neurogenesis in the nucleolus.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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