Thermo Fisher Scientific POLR3F Polyclonal Antibody
POLR3F 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC(Paraffin)에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 POLR3F에 반응하며 HIV 연구 등 RNA Polymerase III 관련 연구에 활용 가능.
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Thermo Fisher Scientific POLR3F Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human POLR3F. Recombinant protein control fragment (Product #RP-99441). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645771 |
Product Specific Information
Immunogen sequence:
CELGISKVEL SMEDIETILN TLIYDGKVEM TIIAAKEGTV GSVDGHMKLY RAVNPIIPPT GLVRAPCGLC PVFDDCHEGG EISPSNCI
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 98%
Target Information
The human POLR3F is a component of RNA polymerase III, which transcribes essential small noncoding RNAs including 5S rRNA and tRNA. Many pol III-transcribed genes are spatially clustered near the nucleolus, potentially coordinating transcription with RNA polymerase I activity.
POLR3F has been identified as an HIV dependency factor (HDF), indicating its potential as a drug target for HIV treatment.
At least two isoforms of POLR3F are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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