Thermo Fisher Scientific DNMT1 Polyclonal Antibody
DNMT1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA, IP, ChIP 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
| ChIP assay (ChIP) | 3 µg antibody for 10–15 µg chromatin |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 760–1109 of DNMT1 (NP_001370.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.87 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914124 |
Product Specific Information
- Positive test controls: Jurkat cells
- Subcellular localization: Nucleus
Immunogen sequence:
GDCVSVIPDD SSKPLYLARV TALWEDSSNG QMFHAHWFCA GTDTVLGATS DPLELFLVDE CEDMQLSYIH SKVKVIYKAP SENWAMEGGM DPESLLEGDD GKTYFYQLWY DQDYARFESP PKTQPTEDNK FKFCVSCARL AEMRQKEIPR VLEQLEDLDS RVLYYSATKN GILYRVGDGV YLPPEAFTFN IKLSSPVKRP RKEPVDEDLY PEHYRKYSDY IKGSNLDAPE PYRIGRIKEI FCPKKSNGRP NETDIKIRVN KFYRPENTHK STPASYHADI NLLYWSDEEA VVDFKAVQGR CTVEYGEDLP ECVQVYSMGG PNRFYFLEAY NAKSKSFEDP PNHARSPGNK
Target Information
This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein interacts with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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