Thermo Fisher Scientific TIMM44 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Positive test controls: U-87MG, K562, mouse liver, rat kidney
• Immunogen sequence:
  AKTAKQSAES VSKGGEKLGR TAAFRALSQG VESVKKEIDD SVLGQTGPYR RPQRLRKRTE FAGDKFKEEK VFEPNEEALG VVLHKDSKWY QQWKDFKENN VVFNRFFEMK MKYDESDNAF IRASRALTDK VTDLLGGLFS KTEMSEVLTE ILRVDPAFDK DRFLKQCEND IIPNVLEAMI SGELDILKDW CYEATYSQLA HPIQQAKALG LQFHSRILDI DNVDLAMGKM MEQGPVLIIT FQAQLVMVVR NPKGEVVEGD PDKVLRMLYV WALCRDQDEL NPYAAWRLLD ISASSTEQIL

Target Information

This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.