Thermo Fisher Scientific GSTA3 Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Positive test controls include: PC-3, 293T, Mouse lung, Mouse liver, Mouse kidney, Rat kidney.

Immunogen sequence:
MAGKPKLHYF NGRGRMEPIR WLLAAAGVEF EEKFIGSAED LGKLRNDGSL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYTEGMA DLNEMILLLP LCRPEEKDAK IALIKEKTKS RYFPAFEKVL QSHGQDYLVG NKLSRADISL VELLYYVEEL DSSLISNFPL LKALKTRISN LPTVKKFLQP GSPRKPPADA KALEEARKIF RF

Target Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. Eight distinct classes of soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta.
This gene encodes a glutathione S-transferase belonging to the alpha class, located on chromosome 6. Alpha class genes encode enzymes with glutathione peroxidase activity but have diverged evolutionarily, resulting in substrate specificity differences. The enzyme catalyzes double bond isomerization of precursors for progesterone and testosterone during steroid hormone biosynthesis.
An additional transcript variant has been identified but its full-length sequence has not been determined.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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