Thermo Fisher Scientific Thrombin Polyclonal Antibody
Rabbit polyclonal antibody recognizing human thrombin (prothrombin). Validated for IHC (paraffin) applications with high specificity. Supplied in liquid form, antigen affinity purified, and stabilized with glycerol. For research use only.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P))
Recommended Dilution
- 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Prothrombin. Recombinant protein control fragment (Product # RP-101519) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856807 |
Product Specific Information
Immunogen sequence:
EGVWCYVAGK PGDFGYCDLN YCEEAVEEET GDGLDEDSDR AIEGRTATSE YQTFFNPRTF GSGEADCGLR PLFEKKSLE
Target Information
Coagulation factor II (prothrombin) is proteolytically cleaved to form thrombin in the first step of the coagulation cascade, which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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