Thermo Fisher Scientific METTL3 Monoclonal Antibody (OTI1B7), TrueMAB
METTL3 단백질을 인식하는 Mouse monoclonal antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 최적화되어 있으며, Lyophilized 형태로 제공됩니다. PBS buffer에 trehalose가 포함되어 안정성이 높습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–284 of human METTL3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
METTL3 is the 70 kDa subunit of MT-A, a component of N6-adenosine-methyltransferase.
This enzyme catalyzes posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine (m6A).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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