Thermo Fisher Scientific CFHR1 Polyclonal Antibody
CFHR1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 적합하며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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- PA5120829
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 151–330 of human CFHR1 (NP_002104.2). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.08 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2914401 |
Product Specific Information
Positive test controls include: LO2, HeLa, NCI-H460, Mouse liver, Mouse lung, Mouse heart, Rat liver.
The target is usually found in the following locations: Secreted.
Immunogen sequence:
PTVQNAHILS RQMSKYPSGE RVRYECRSPY EMFGDEEVMC LNGNWTEPPQ CKDSTGKCGP PPPIDNGDIT SFPLSVYAPA SSVEYQCQNL YQLEGNKRIT CRNGQWSEPP KCLHPCVISR EIMENYNIAL RWTAKQKLYL RTGESAEFVC KRGYRLSSRS HTLRTTCWDG KLEYPTCAKR
Target Information
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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