Thermo Fisher Scientific IGF2BP3 Polyclonal Antibody
IGF2BP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며 Human, Mouse, Rat 반응성. 액상 형태로 1.25 mg/mL 농도, -20°C에서 보관. 세포 내 Cytoplasm과 Nucleus에서 발현 확인 가능.
- 카탈로그번호
- PA5120830
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IGF2BP3 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–200 of human IGF2BP3 (NP_006538.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.25 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914402 |
Product Specific Information
- Positive test controls: HeLa, BxPC-3, SGC-7901, NIH/3T3, 293T, HepG2
- Target localization: Cytoplasm, Nucleus
Immunogen sequence:
MNKLYIGNLS ENAAPSDLES IFKDAKIPVS GPFLVKTGYA FVDCPDESWA LKAIEALSGK IELHGKPIEV EHSVPKRQRI RKLQIRNIPP HLQWEVLDSL LVQYGVVESC EQVNTDSETA VVNVTYSSKD QARQALDKLN GFQLENFTLK VAYIPDEMAA QQNPLQQPRG RRGLGQRGSS RQGSPGSVSK QKPCDLPLRL
Target Information
Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family. It is expressed during embryogenesis and in certain malignancies.
IMP-3 is expressed in malignant melanoma but not in benign nevi, even with dysplastic features. It is found more frequently in melanomas than Spitz nevi and more in metastatic melanomas than in thin melanomas.
IMP-3 may play an important role in the progression and biological behavior regulation of malignant melanoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-120830_IGF2BP3_O00425-1_Rabbit.svg)
(이미지: PA5-120830_IGF2BP3_O00425-1_Rabbit_PDP.jpeg)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.